Geyer FC, de Biase D, Lambros MB, Ragazzi M, Lopez-Garcia MA, Natrajan R, Mackay A, Kurelac I, Gasparre G, Ashworth A, Eusebi V, Reis-Filho JS, Tallini G.
Genomic profiling of mitochondrion-rich breast carcinoma: chromosomal changes may be relevant for mitochondria accumulation and tumour biology.
Breast Cancer Res Treat. 2012 Feb;132(1):15-28.
Albanell J, González A, Ruiz-Borrego M, Alba E, García-Saenz JA, Corominas JM, Burgues O, Furio V, Rojo A, Palacios J, Bermejo B, Martínez-García M, Limon ML, Muñoz AS, Martín M, Tusquets I, Rojo F, Colomer R, Faull I, Lluch A.
Prospective transGEICAM study of the impact of the 21-gene Recurrence Score assay and traditional clinicopathological factors on adjuvant clinical decision making in women with estrogen receptor-positive (ER+) node-negative breast cancer.
Ann Oncol. 2012 Mar;23(3):625-31.
Castilla MÁ, Moreno-Bueno G, Romero-Pérez L, Van De Vijver K, Biscuola M, López-García MÁ, Prat J, Matías-Guiu X, Cano A, Oliva E, Palacios J.
Micro-RNA signature of the epithelial-mesenchymal transition in endometrial carcinosarcoma.
J Pathol. 2011 Jan;223(1):72-80.
Dedes KJ, Natrajan R, Lambros MB, Geyer FC, Lopez-Garcia MA, Savage K, Jones RL, Reis-Filho JS.
Down-regulation of the miRNA master regulators Drosha and Dicer is associated with specific subgroups of breast cancer.
Eur J Cancer. 2011 Jan;47(1):138-50.
Badve S, Dabas DJ, Schnitt SJ, Baehner FL, Decaer T, Eusebi V, Fox SB, Ichihara S, Jacquemier J, Lakhani SR, Palacios J, Rakha EA, Richardson AL, Schmitt FC, Tan PH, Tse GM, Weigelt B, Ellis IO, Reis-Filho JS.
Basal-like and triple-negative breast cancers: a critical review with an emphasis on the implications for pathologists and oncologists.
Mod Pathol. 2011 Feb; 24(2):157-67.
Nicolae A, Preda O, Aneiros-Fernández J, Palacios J, Biscuola M, Nogales FF.
p16(INK4A) positivity identifies endometrial surface papillary syncitial change as a regressive feature associated with desquamation.
Histopathology. 2011 Feb;58(3):483-6.
Llobet D, Eritja N, Domingo M, Bergada L, Mirantes C, Santacana M, Pallares J, Macià A, Yeramian A, Encinas M, Moreno-Bueno G, Palacios J, Lewis RE, Matias-Guiu X, Dolcet X.
KSR1 is overexpressed in endometrial carcinoma and regulates proliferation and TRAIL-induced apoptosis by modulating FLIP levels.
Am J Pathol. 2011 Apr;178(4):1529-43.
Vieites B, Avila R, Biscuola M, Carvajo F.
Cutaneous Hodgkin-type lymphoproliferative lesion associated with immunomodulatory therapy for ulcerative colitis.
J Cutan Pathol. 2011 May;38(5):443-7.
Bernet L, Cano R, Martinez M, Dueñas B, Matias-Guiu X, Morell L, Palacios J, Rezola R, Robles-Frias M, Ruiz I, Velasco A, Vieites B, Sevilla F, Torro J, Medrano J, Ballester B.
Diagnosis of the sentinel lymph node in breast cancer: a reproducible molecular method: a multicentric Spanish study.
Histopathology. 2011 May;58(6):863-9.
Moreno-Bueno G, Salvador F, Martín A, Floristán A, Cuevas EP, Santos V, Montes A, Morales S, Castilla MA, Rojo-Sebastián A, Martínez A, Hardisson D, Csiszar K, Portillo F, Peinado H, Palacios J, Cano A.
Lysyl oxidase-like 2 (LOXL2), a new regulator of cell polarity required for metastatic dissemination of basal-like breast carcinomas.
EMBO Mol Med. 2011 Sep;3(9):528-44.
Gómez-Martín C, Concha A, Corominas JM, García-Caballero T, García-García E, Iglesias M, López JA, Ramón y Cajal S, Rojo F, Palacios J, Vera-Sempere F, Aranda E, Colomer R, García-Alfonso P, Garrido P, Rivera F, López-Ríos F; Spanish Society of Medical Oncology; Spanish Society of Pathology.
Consensus of the Spanish Society of Medical Oncology (SEOM) and Spanish Society of Pathology (SEAP) for HER2 testing in gastric carcinoma.
Clin Transl Oncol. 2011 Sep;13(9):636-51.
Turner N, Pearson A, Sharpe R, Lambros M, Geyer F, Lopez-Garcia MA, Natrajan R, Marchio C, Iorns E, Mackay A, Gillett C, Grigoriadis A, Tutt A, Reis-Filho JS, Ashworth A.
FGFR1 amplification drives endocrine therapy resistance and is a therapeutic target in breast cancer.
Cancer Res. 2010 Mar 1;70(5):2085-94.
Weigelt B, Geyer FC, Natrajan R, Lopez-Garcia MA, Ahmad AS, Savage K, Kreike B, Reis-Filho JS.
The molecular underpinning of lobular histological growth pattern: a genome-wide transcriptomic analysis of invasive lobular carcinomas and grade- and molecular subtype-matched invasive ductal carcinomas of no special type.
J Pathol. 2010 Jan;220(1):45-57.
Abdel-Fatah TM, Powe DG, Agboola J, Adamowicz-Brice M, Blamey RW, Lopez-Garcia MA, Green AR, Reis-Filho JS, Ellis IO.
The biological, clinical and prognostic implications of p53 transcriptional pathways in breast cancers.
J Pathol. 2010 Mar;220(4):419-34.
Lopez-Garcia MA, Geyer FC, Natrajan R, Kreike B, Mackay A, Grigoriadis A, Reis-Filho JS, Weigelt B.
Transcriptomic analysis of tubular carcinomas of the breast reveals similarities and differences with molecular subtype-matched ductal and lobular carcinomas.
J Pathol. 2010 Sep;222(1):64-75.
Abdel-Fatah TM, Powe DG, Ball G, Lopez-Garcia MA, Habashy HO, Green AR, Reis-Filho JS, Ellis IO.
Proposal for a modified grading system based on mitotic index and Bcl2 provides objective determination of clinical outcome for patients with breast cancer.
J Pathol. 2010 Dec;222(4):388-99.
Rakha EA, Reis-Filho JS, Baehner F, Dabbs DJ, Decker T, Eusebi V, Fox SB, Ichihara S, Jacquemier J, Lakhani SR, Palacios J, Richardson AL, Schnitt SJ, Schmitt FC, Tan PH, Tse GM, Badve S, Ellis IO.
Breast cancer prognostic classification in the molecular era: the role of histological grade.
Breast Cancer Res. 2010;12(4):207.
Klingbeil P, Natrajan R, Everitt G, Vatcheva R, Marchio C, Palacios J, Buerger H, Reis-Filho JS, Isacke CM.
CD44 is overexpressed in basal-like breast cancers but is not a driver of 11p13 amplification.
Breast Cancer Res Treat. 2010 Feb;120(1):95-109.
Natrajan R, Weigelt B, Mackay A, Geyer FC, Grigoriadis A, Tan DS, Jones C, Lord CJ, Vatcheva R, Rodriguez-Pinilla SM, Palacios J, Ashworth A, Reis-Filho JS.
An integrative genomic and transcriptomic analysis reveals molecular pathways and networks regulated by copy number aberrations in basal-like, HER2 and luminal cancers.
Breast Cancer Res Treat. 2010 Jun;121(3):575-89.
Dedes KJ, Lopez-Garcia MA, Geyer FC, Lambros MB, Savage K, Vatcheva R, Wilkerson P, Wetterskog D, Lacroix-Triki M, Natrajan R, Reis-Filho JS.
Cortactin gene amplification and expression in breast cancer: a chromogenic in situ hybridisation and immunohistochemical study.
Breast Cancer Res Treat. 2010 Dec;124(3):653-66.
Muñoz M, Rosso M, Robles-Frias MJ, Salinas-Martín MV, Rosso R, González-Ortega A, Coveñas R.
The NK-1 receptor is expressed in human melanoma and is involved in the antitumor action of the NK-1 receptor antagonist aprepitant on melanoma cell lines.
Lab Invest. 2010 Aug;90(8):1259-69.
Lambros MB, Natrajan R, Geyer FC, Lopez-Garcia MA, Dedes KJ, Savage K, Lacroix-Triki M, Jones RL, Lord CJ, Linardopoulos S, Ashworth A, Reis-Filho JS.
PPM1D gene amplification and overexpression in breast cancer: a qRT-PCR and chromogenic in situ hybridization study.
Mod Pathol. 2010 Oct;23(10):1334-45.
Caffarel MM, Andradas C, Mira E, Pérez-Gómez E, Cerutti C, Moreno-Bueno G, Flores JM, García-Real I, Palacios J, Mañes S, Guzmán M, Sánchez C.
Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition.
Mol Cancer. 2010 Jul 22;9:196.
Lopez-Garcia MA, Geyer FC, Lacroix-Triki M, Marchió C, Reis-Filho JS.
Breast cancer precursors revisited: molecular features and progression pathways.
Histopathology. 2010 Aug;57(2):171-92.
Suárez-Peñaranda JM, Vieites B, Valeiras E, Varela-Duran J.
Primary mucoepidermoid carcinoma of the skin expressing p63.
Am J Dermatopathol. 2010 Feb;32(1):61-4.
Lopez-Garcia MA, Palacios J.
Pathologic and molecular features of uterine carcinosarcomas.
Semin Diagn Pathol. 2010 Nov;27(4):274-86.
Melchor L, Saucedo-Cuevas LP, Muñoz-Repeto I, Rodríguez-Pinilla SM, Honrado E, Campoverde A, Palacios J, Nathanson KL, García MJ, Benítez J
Comprehensive characterization of the DNA amplification at 13q34 in human breast cancer reveals TFDP1 and CUL4A as likely candidate target genes.
Breast Cancer Research: BCR 2009 ;11(6):R86
Natrajan R, Lambros MB, Rodríguez-Pinilla SM, Moreno-Bueno G, Tan DS, Marchió C, Vatcheva R, Rayter S, Mahler-Araujo B, Fulford LG, Hungermann D, Mackay A, Grigoriadis A, Fenwick K, Tamber N, Hardisson D, Tutt A, Palacios J, Lord CJ, Buerger H, Ashworth A, Reis-Filho JS
Tiling path genomic profiling of grade 3 invasive ductal breast cancers.
Clin Cancer Res. 2009 Apr 15;15(8):2711-22.
Moreno-Bueno G, Peinado H, Molina P, Olmeda D, Cubillo E, Santos V, Palacios J, Portillo F, Cano A
The morphological and molecular features of the epithelial-to-mesenchymal transition.
Nature protocols 2009 ;4(11):1591-613
Neria F, Castilla MA, Sanchez RF, Gonzalez Pacheco FR, Deudero JJ, Calabia O, Tejedor A, Manzarbeitia F, Ortiz A, Caramelo C
Inhibition of JAK2 protects renal endothelial and epithelial cells from oxidative stress and cyclosporin A toxicity.
Kidney Int. 2009 Jan;75(2):227-34. FI: 6.418
Cuatrecasas M, Catasus L, Palacios J, Prat J
Transitional cell tumors of the ovary: a comparative clinicopathologic, immunohistochemical, and molecular genetic analysis of Brenner tumors and transitional cell carcinomas.
The American journal of surgical pathology 2009 Apr;33(4):556-67
Geyer JT, López-García MA, Sánchez-Estevez C, Sarrió D, Moreno-Bueno G, Franceschetti I, Palacios J, Oliva E
Pathogenetic pathways in ovarian endometrioid adenocarcinoma: a molecular study of 29 cases.
The American journal of surgical pathology 2009 Aug;33(8):1157-63
Cagnin S, Biscuola M, Patuzzo C, Trabetti E, Pasquali A, Laveder P, Faggian G, Iafrancesco M, Mazzucco A, Pignatti PF, Lanfranchi G
Reconstruction and functional analysis of altered molecular pathways in human atherosclerotic arteries.
BMC genomics 2009 ;10():13
Natrajan R, Lambros MB, Geyer FC, Marchio C, Tan DS, Vatcheva R, Shiu KK, Hungermann D, Rodriguez-Pinilla SM, Palacios J, Ashworth A, Buerger H, Reis-Filho JS
Loss of 16q in high grade breast cancer is associated with estrogen receptor status: Evidence for progression in tumors with a luminal phenotype?
Genes, chromosomes & cancer 2009 Apr;48(4):351-65
Mendiola M, Barriuso J, Mariño-Enríquez A, Redondo A, Domínguez-Cáceres A, Hernández-Cortés G, Pérez-Fernández E, Sánchez-Navarro I, Vara JA, Suárez A, Espinosa E, González-Barón M, Palacios J, Hardisson D
Aurora kinases as prognostic biomarkers in ovarian carcinoma.
Human pathology 2009 May;40(5):631-8
Sarrió D, Palacios J, Hergueta-Redondo M, Gómez-López G, Cano A, Moreno-Bueno G
Functional characterization of E- and P-cadherin in invasive breast cancer cells.
BMC cancer 2009 ;9():74
Sarrió D, Rodriguez-Pinilla SM, Hardisson D, Cano A, Moreno-Bueno G, Palacios J
Epithelial-mesenchymal transition in breast cancer relates to the basal-like phenotype.
Cancer research 2008 Feb;68(4):989-97
Melchor L, Honrado E, García MJ, Alvarez S, Palacios J, Osorio A, Nathanson KL, Benítez J
Distinct genomic aberration patterns are found in familial breast cancer associated with different immunohistochemical subtypes.
Oncogene 2008 May;27(22):3165-75
Honrado E, Osorio A, Milne RL, Paz MF, Melchor L, Cascón A, Urioste M, Cazorla A, Díez O, Lerma E, Esteller M, Palacios J, Benítez J
Immunohistochemical classification of non-BRCA1/2 tumors identifies different groups that demonstrate the heterogeneity of BRCAX families.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2007 Dec;20(12):1298-306
Hernández-Vargas H, Rodríguez-Pinilla SM, Julián-Tendero M, Sánchez-Rovira P, Cuevas C, Antón A, Ríos MJ, Palacios J, Moreno-Bueno G
Gene expression profiling of breast cancer cells in response to gemcitabine: NF-kappaB pathway activation as a potential mechanism of resistance.
Breast cancer research and treatment 2007 Apr;102(2):157-72
Rodríguez-Pinilla SM, Sarrió D, Honrado E, Moreno-Bueno G, Hardisson D, Calero F, Benítez J, Palacios J
Vimentin and laminin expression is associated with basal-like phenotype in both sporadic and BRCA1-associated breast carcinomas.
Journal of clinical pathology 2007 Sep;60(9):1006-12
Hernández-Vargas H, Palacios J, Moreno-Bueno G
Molecular profiling of docetaxel cytotoxicity in breast cancer cells: uncoupling of aberrant mitosis and apoptosis.
Oncogene 2007 May;26(20):2902-13
Rodríguez-Pinilla SM, Rodríguez-Gil Y, Moreno-Bueno G, Sarrió D, Martín-Guijarro Mdel C, Hernandez L, Palacios J
Sporadic invasive breast carcinomas with medullary features display a basal-like phenotype: an immunohistochemical and gene amplification study.
The American journal of surgical pathology 2007 Apr;31(4):501-8
Alonso SR, Tracey L, Ortiz P, Pérez-Gómez B, Palacios J, Pollán M, Linares J, Serrano S, Sáez-Castillo AI, Sánchez L, Pajares R, Sánchez-Aguilera A, Artiga MJ, Piris MA, Rodríguez-Peralto JL
A high-throughput study in melanoma identifies epithelial-mesenchymal transition as a major determinant of metastasis.
Cancer research 2007 Apr;67(7):3450-60
Hernández-Vargas H, Palacios J, Moreno-Bueno G
Telling cells how to die: docetaxel therapy in cancer cell lines.
Cell cycle (Georgetown, Tex.) 2007 Apr;6(7):780-3
Rodriguez-Pinilla SM, Sarrio D, Moreno-Bueno G, Rodriguez-Gil Y, Martinez MA, Hernandez L, Hardisson D, Reis-Filho JS, Palacios J
Sox2: a possible driver of the basal-like phenotype in sporadic breast cancer.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2007 Apr;20(4):474-81
Moreno-Bueno G, Fernandez-Marcos PJ, Collado M, Tendero MJ, Rodriguez-Pinilla SM, Garcia-Cao I, Hardisson D, Diaz-Meco MT, Moscat J, Serrano M, Palacios J
Inactivation of the candidate tumor suppressor par-4 in endometrial cancer.
Cancer research 2007 Mar;67(5):1927-34
Climent J, Dimitrow P, Fridlyand J, Palacios J, Siebert R, Albertson DG, Gray JW, Pinkel D, Lluch A, Martinez-Climent JA
Deletion of chromosome 11q predicts response to anthracycline-based chemotherapy in early breast cancer.
Cancer research 2007 Jan;67(2):818-26
Hernández-Vargas H, von Kobbe C, Sánchez-Estévez C, Julián-Tendero M, Palacios J, Moreno-Bueno G
Inhibition of paclitaxel-induced proteasome activation influences paclitaxel cytotoxicity in breast cancer cells in a sequence-dependent manner.
Cell cycle (Georgetown, Tex.) 2007 Nov;6(21):2662-8
Mª José Robles-Frías, Felicia Sánchez-Gallego, Michele Biscuola, Mª Ángeles Castilla, Laura Romero, Mª Ángeles López, José Palacios. Editores: Editores Jorge García Tamayo y Eduardo Blasco-Olaetxea.
Tumor de Wilms: Patología Molecular y Manejo Actual
En AVANCES EN PATOLOGÍA. LA PATOLOGÍA DEL CÁNCER. Pg: 151-162. Editorial Cabildo de Fuerteventura. Fuerteventura. España. 2009. ISBN: 978-84-96017-65-8
Mª Ángeles Castilla, Laura Romero, Mª José Robles-Frías, Michele Biscuola, Mª Ángeles López, José Palacios. Editores: Editores Jorge García Tamayo y Eduardo Blasco-Olaetxea.
Patología Molecular del Cáncer de Mama Hereditario
En AVANCES EN PATOLOGÍA. LA PATOLOGÍA DEL CÁNCER. Pg: 115-128. Editorial Cabildo de Fuerteventura. Fuerteventura. España. 2009. ISBN: 978-84-96017-65-8
David Olmeda, Gema Moreno-Bueno, David Sarrió, José Palacios and Amparo Cano
Invasion Program of Normal And Cancer Stem Cells
En CANCER STEM CELLS. IDENTIFICATION AND TARGETS. Pg: 167-195. Edited by Sharmila Bapat. John Wiley & Sons. New Jersey. EEUU. ISBN: 978-0-470-12201-3
